Preimplantation genetic diagnosis (PGD) is used to reduce the risk or avoid transmission of a genetic disease or chromosomal abnormality. PGD can be used by couples who have, or have a family history of, a genetic disease or chromosomal abnormality that they risk passing on to their children. PGD is also used for couples who have had repeated miscarriages or repeated IVF failure and also for women of advanced maternal age (generally over 36-38 years of age).
In PGD, embryos are generated through the process of IVF or ICSI and then one or two cells are removed from the embryo and are screened for a genetic condition. Embryos unaffected by a particular genetic condition may then be selected for transfer to the woman's uterus.
What is preimplantation genetic diagnosis?
Assisted reproductive treatment clinics in Victoria perform PGD to reduce the risk of, or to avoid a range of conditions.
Sex selection can be performed in Victoria only to reduce the risk of transmission of a genetic disease or abnormality to a child. Sex selection may be performed to reduce the risk of transmission of a disorder linked to an X chromosome (such as Muscular Dystrophy or Haemophilia) or for a condition that occurs more frequently in one sex but where the genetic cause is unknown (e.g. autism).
Aneuploidy is a term used to describe an abnormality in chromosome number (fewer or more of a specific chromosome). Aneuploidy screening is performed in cases of advanced maternal age, repeated IVF failure, recurrent miscarriage and previous aneuploidy pregnancy.
If there is a disorder that you are particularly concerned about, contact your ART clinic.